NJ Immunization Information System (NJIIS) – The Registry
The New Jersey Immunization Information System (NJIIS) is a secure web-based program
health care providers can use to track the vaccines they administer in their office or view
vaccines other providers have administered. NJIIS serves as the official repository of
Immunizations administered to children in New Jersey.
NJIIS is the official Immunization Registry per the Statewide Immunization Registry Act –
NJAC 8:57 – 3. Any health care provider who administers vaccines to children less than 7 years
of age is state mandated to enter these vaccines into NJIIS according to NJAC 8:57 – 3.16.
NJIIS is not only for children, it is a life span Registry. Any person who was born prior to
January 1, 1998 can be enrolled in NJIIS at their health care provider (HCP) as long as they give
consent to be part of NJIIS.
Provider Trainings: Providers in Central NJ (Hunterdon, Mercer, Middlesex, Monmouth, Ocean
and Somerset Counties) are trained to manually enter vaccines into NJIIS. School Nurses are
trained to view the information in NJIIS for their students and Advanced Webinars are conducted
for the existing NJIIS users to learn additional functions in the system.
Quality Assurance (QA): QA Specialists conduct routine audits of the providers’ data currently
enrolled in NJIIS, comparing provider’s medical record for their patients to the information in
NJIIS. Discrepancies are reported to the provider with instructions on how to complete the
Online Immunization Record. The QA Specialists also routinely merge duplicate patients, reset
passwords for existing NJIIS users and answer general questions from providers.
For more information regarding NJIIS and how the program can benefit your practice please
contact the NJIIS Program Coordinator/Trainer 732-937-5437.
Interfaces Management System (IMS):
The NJIIS Interface Management System (IMS) was implemented to facilitate the electronic
movement of health-related information between NJIIS and other authorized organizations
according to nationally recognized standards. The IMS is a bidirectional interoperable system
which expedites data exchange using Health Level 7 (HL7) standards.
Please refer to the getting started guide for information on how to interface with NJIIS Interface
Please refer to the NJIIS IMS Local Implementation Guide (IG) for detailed specifications for
creating and formatting your HL7 2.5.1 messages. The Local IG also contains sample messages
for your reference.
Once you have reviewed the Local IG and created your test HL7 messages, please click here to
smoke test your HL7 messages per NJIIS IG. The NJIIS HL7 Smoke Test will only test the
structure of your HL7 message to ensure it meets the specifications of the Local IG and not the
actual data content.
The NJIIS IMS supports Unsolicited Vaccination Update (VXU) message for inbound
transactions and sends out an acknowledgement (ACK) for each HL7 2.5.1 VXU message
received. IMS supports Query By Parameter (QBP) message for outbound transactions and
responds with a Query Response (RSP) message for each HL7 2.5.1 QBP message received.
The NJIIS IMS Gateway exposes a web service to external systems. The web service includes
operations to synchronously receive, process, and respond to a single HL7 message. The HL7
messages should be transmitted to the web service deployed in the gateway using SOAP
For additional information, including the “Getting Started: How to establish an HL7 interface
with NJIIS” document, click here.
Vaccine Preventable Diseases:
The NJIIS staff works with the NJDOH's Vaccine Preventable Disease Program on educating
professionals and consumers in the prevention of Human Papilloma Virus (HPV) associated
cancers and the dissemination of HPV materials for health care providers throughout our service
region. In addition, you can access NJIIS on-demand tutorials for Reminder Recall (current users
can learn about NJIIS Reminder Recall functionality) and for use of the HPV Vaccination Tool
(intended for health care providers who administer adolescent immunizations; provides
important reminders on how to improve HPV vaccination rates, tips for talking to parents about
the vaccine, as well as a vaccination dose assessment table). HPV is the most common sexually
transmitted infection. It is recommended that adolescents get vaccinated by 11-12 years of age,
and can be vaccinated as early as 9 years of age. With the high rates of HPV associated cancers
and low HPV vaccine coverage rates in NJ, there is a need for continued education on HPV
vaccination to prevent cancer including HPV prevalence and current ACIP HPV vaccine
recommendations. If you are interested in receiving materials or want HPV education for your
clients or staff, the Director of Child and Adolescent Health at 732-937-5437.